The only special care long haired Syrian hamsters need is that they may get bedding stuck in thier fur and sometimes it can be soiled bedding. You need a small comb to remove any bedding. Be gentle, hamsters can be injured easily. If they get knots in thier fur do not comb through it remove the comb. You should alos use a fine tooth brush to check for any bugs. Brush through your hamster's fur, then rub the comb on a peice of white paper, if you see small black specks your hamster may have mites. They will also itch a lot and experience fur loss.